Description

Drostanolone propionate, commonly known by the trade name Masteron, is an injectable anabolic-androgenic steroid (AAS) derived from dihydrotestosterone (DHT). It is modified to resist breakdown by the aromatase enzyme, which means it does not convert to estrogen in the body. This makes it distinct from many other testosterone-derived compounds.

Originally, drostanolone was used in medicine, particularly in the treatment of advanced breast cancer in women, due to its anti-estrogenic properties. Today, its medical use is rare, and it is primarily known in the context of doping and bodybuilding.

Pharmacology:

• Form: Injectable solution (intramuscular)

• Ester: Propionate (short-acting)

• Half-life: ~2–3 days

• Class: DHT-derived anabolic steroid

• Properties: Non-aromatizing, moderate anabolic and androgenic activity

Key Characteristics:

• Does not convert to estrogen → reduced risk of water retention or gynecomastia

• Used historically for certain cancers due to its anti-estrogenic effects

• Known for producing a “hardening” effect on muscle appearance (non-medical context)